Most people come into the world with a maximum weight of 4 kg and a height of 50-52 cm. During life, these parameters evolve, for which the growth hormone, or somatotropin, is responsible. Before considering the specifics of the action of this hormone on the human body, we need to look at the history of its discovery.
Growth hormone was discovered in the 20s of the 20th century, and in 1944 it was crystallized from the pituitary gland of animals. Human somatotropin was isolated in 1956, and in 1958 it was given to a child whose body did not produce it. Thanks to this therapy, the child began to grow, which prompted similar applications of the hormone in the future. On this site you can always buy growth hormone pharmacy at the best price in France
How was somatotropin obtained?
However, a problem soon arose as to how the hormone was obtained. The only source of somatotropin at the time was the brains of deceased people. To get a few drops of the hormone, thousands of brains were needed. The cadaveric material came from Africa and during the production process of somatotropin the material was not sterilized but pasteurized, the somatotropin being destroyed by heat. Subsequently, many children who received this hormone developed a rare viral disease, which is why this method of producing somatotropin was banned.
It was therefore necessary to artificially synthesize somatotropin, which was not an easy task, since growth hormone consists of 191 amino acids. The situation was saved by genetic engineering in the 80s of the 20th century, which provided methods for cloning human proteins. Somatotropin was synthesized in 1985.
What is somatotropin?
Somatotropin is a polypeptide hormone produced by the body’s largest gland, the pituitary gland, located in the anterior lobe. It contains 191 amino acid residues. Somathropin is primarily responsible for growth, and the greatest amount of this hormone is secreted at night. That’s why babies and young children need lots of sleep to develop. After being released into the bloodstream, growth hormone reaches the liver, where it is transformed into insulin-like growth factor 1 (IGF-1).
IGF-1 is responsible for growth hormone activity in the body. However, the growth of the organism does not always occur at a regular rate, but rather by growth spurts. The first growth spurt occurs early in life and lasts about two years. The second growth spurt occurs during the preschool years and the third during adolescence. And even when growth hormone production slows, it continues to affect our physical and mental condition. The slowdown in the production of growth hormone begins at the age of 20, and according to the calculations of scientists, its level decreases by 15% every ten years. No wonder the majority of people in their 60s only produce 25% of growth hormone.
Applications of somatotropin
Growth hormone is often called the “youth hormone”: it is often used as part of anti-aging therapy. Many celebrities resort to growth hormone rejuvenation procedures and benefit from increased muscle mass and vitality, improved physical and mental performance, increased libido, better skin condition and general well-being.
Of course, the ability of growth hormone to increase muscle mass and promote fat burning is interesting for athletes. The bodybuilding world, for example, discovered growth hormone in the early 1980s, and its appearance had a significant impact on the successful development of this sport. Athletes of the time were strikingly different from those building their bodies in the 1970s, before the introduction of growth hormone. Many athletes see a difference after taking growth hormone before after
Functions of growth hormone:
- Stimulates division and multiplication of cartilage cells;
- Promotes calcium retention and bone mineralization;
- Stimulates cell growth in all organs of our body;
- Improves metabolism;
- Regenerates damaged cells;
The production of growth hormone has a positive effect on the whole body. It strengthens the immune system, stimulates muscle and bone growth and promotes the reduction of fat stores, which explains its popularity among athletes.