Both zopiclone and nitrazepam are used to treat insomnia and help you to sleep. Although the two medications serve a similar purpose – giving you a quality sleep – they are slightly different: nitrazepam is a benzodiazepine, which is a type of medication that soothes you to sleep. It is available in tablet and oral liquid. Doctors normally prescribe it for patients who cannot get good quality sleep due to anxiety.
On the other hand, zopiclone is a non-benzodiazepine. This class of medications is recommended or normally prescribed for patients suffering from insomnia. The zopiclone tablet contains 7.5 mg of zopiclone. The good news about zopiclone is that it helps a patient enjoy a seven to eight-hours uninterrupted sleep, which is pleasant if you have difficulties in falling asleep, awake early, and if your insomnia is becoming unbearable.
How Are Zopiclone and Nitrazepam Taken?
Nitrazepam must be taken with food. Since it is available in tablet and oral liquid, it is convenient if you are irritated by swallowing tablets or dislike some bitter pills. The nitrazepam usual dose is 5mg before going to bed. Your dose could be more or less than this. Your doctor may recommend that you take a dose for just a few days or only on certain days. With zopiclone, each tablet must be swallowed without crashing or chewing it just before retiring to bed. You can take it with or without food.
You are advised not to use both medications for a long time because they are habit-forming and prolonged use may lead to dependence on the drugs. In addition, if you shorten the duration of use of these drugs, you lower the risk of addiction. It is also recommended that you minimize the dose and ensure that it is low, as long as it is effective; do not be tempted to use more for maximum results.
For zopiclone, most medical practitioners recommend a dose of 7.5mg with water before sleep and 5mg of nitrazepam, but it can be increased to 10mg if there is a need.
Both medications can be used by the elderly because they can take a dose of 3.75. Your doctor can assess the effectiveness of the dosage and if it is not effective, it can be increased. Zopiclone is accessible to more people even those with conditions such as hepatic dysfunction. The recommended dosage for such patients is 3.5mg. Similarly, patients with liver disease and renal failure can use nitrazepam.
Zopiclone and nitrazepam must be used cautiously if they are used in conjunction with other drugs, like opioids. They may not work properly when taken together and such use may lead to adverse effects.
How Do These Medications Work?
The two medications work in the receptors of the brain which are responsible for keeping your body alert and making it relax. They relax the brain, thus allowing you to sleep. In addition, they slow down the movement of nerves in the brain. The chemicals they release also control the way you normally sleep or awake. This has a calming, energizing and relaxing effect.
Furthermore, nitrazepam shortens the time required to fall asleep. It acts within 30-60 minutes. However, zopiclone takes an hour to work in your system, but does not stay in your body for a longer time.
What Are the Durations of Action of Zopiclone and Nitrazepam?
You can treat insomnia with zopiclone for a few days, preferably a week, which makes the duration of the treatment shorter. It can last for a few days to a maximum of four weeks if a doctor recommends it. If you use nitrazepam for a brief period, it is effective. For some patients, a three weeks’ treatment may be necessary. The maximum duration of treatment with nitrazepam is four weeks; these include the time when the patient is slowly withdrawing from the drug.
If a patient takes nitrazepam for a longer period, the drug may cease to have the desired effect. In addition, if you stop using it abruptly, it is possible to show withdrawal symptoms. If this occurs, your doctor may recommend that you continue using the medication to prevent these symptoms.
When using zopiclone, the risk of dependence on the drug increases with alcohol and substance abuse. Similarly, nitrazepam must be used cautiously for patients who have a history of drug or alcohol abuse. If you start depending on the drug, your doctor may recommend that you discontinue the treatment.
With nitrazepam, sometimes your doctor may recommend that you reduce your dose gradually when it is time to stop taking it. This is to reduce the risk of your experiencing withdrawal side effects.
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